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Avanti Polar
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Image Search Results
Journal: Journal of Cellular and Molecular Medicine
Article Title: Human Placental Mesenchymal Stem/Stromal cells (pMSCs) inhibit agonist‐induced platelet functions reducing atherosclerosis and thrombosis phenotypes
doi: 10.1111/jcmm.16848
Figure Lengend Snippet: pMSCs demonstrate differential expression of genes involved in coagulation and thrombosis: Real‐time PCR analysis (RT‐PCR) analysis of pro‐ and anti‐thrombotic genes expressed in pMSCs in comparison to HUVECs. (A) Genes inhibiting thrombosis and coagulation. TFPAI (Tissue Factor Pathway Inhibitor), PROC1 (Vitamin K‐dependent protein C1), PROS1 (Protein S1), SERPINC1 (Serpin Family C Member 1) and THBS4 (Thrombospondin 4). (B) Genes promoting thrombosis and coagulation. vWF (Von Willebrand Factor), GP6 (Glycoprotein VI platelet), PLCG2 (Phospholipase C Gamma 2), GRK5 (G Protein‐Coupled Receptor Kinase 5) and PLEK (Pleckstrin). Three independent experiments were performed for each cell type isolated from three different placentae. The data are expressed as fold change difference calculated from the ΔΔ −2 values. Bars represent mean ± SE. * p ≤ 0.05
Article Snippet: Primary antibodies to Human GP VI (cat# AF3627);
Techniques: Quantitative Proteomics, Coagulation, Real-time Polymerase Chain Reaction, Reverse Transcription Polymerase Chain Reaction, Comparison, Isolation